PUBLICATIONS

Year 2017

  • Advances in transgenic animal models and techniques
  • Transgenic Research 2017.
  • S. Ménoret , L. Tesson, S. Rémy, C. Usal, L.-H. Ouisse, L. Brusselle, V. Chenouard, I. Anegon
  • Cell-surface C-type lectin-like receptor CLEC-1 dampens dendritic cell activation and downstream Th17 responses
  •  Blood Adv. 2017. In press
  • M.-D. Lopez Robles, A. Pallier, V. Huchet, L. Le Texier, S. Rémy, C. Braudeau, L. Delbos, A. Moreau, C. Louvet, C. Brosseau, P.-J. Royer, A. Magnan, F. Halary, R. Josien, M.-C. Cuturi, I. Anegon & E. Chiffoleau
  • Heme-oxygenase-1 expression contributes to the immunoregulation induced by Fasciola hepatica and promotes infection
  •  Frontiers in immunology 2017. In press
  • P. Carasi, E. Rodriguez, V. da Costa, S. Frigerio, N. Brossard, V. Noya, C. Robello, I. Anegon and T. Freire
  • Immunoregulatory properties of the cytokine Il-34
  •  Cellular and Molecular Life Sciences 2017. In press
  • C. Guillonneau, S. Bézie, I. Anegon
  • Inhibition of effector antigen-specific T cells by intradermal administration of heme-oxygenase-1 inducers
  •  J. Autoimmun. 2017. In press
  • T. Simon, J. Pogu, S. Rémy, F. Brau, S. Pogu, M. Maquigneau, J.-F. Fonteneau, B. Vanhove, G. Blancho, E. Piaggio, I. Anegon & P. Blancou
  • Blood biomarkers of kidney transplant rejection, an endless search
 Expert Rev. Mol. Diagn. 2017. In press

Lola Jacquemont, Jean-Paul Soulillou and Nicolas Degauque

  • Dysregulated responsiveness of circulating dendritic cells to Toll-like receptors in ANCA-associated vasculitis
 Front. Immunol 2017. In press

C. Braudeau, A. Neel, K. Amouriaux, JC Martin, M. Rimbert, A. Besançon, S. Giraudet, C. Terrien, M. Aliaga, N. Salabert-Le Guen, C. Hémont, M. Hamidou, R. Josien

Year 2016

  • The phosphorylation of Metaxin 1 controls Bak activation during TNFα induced cell death
OCellular Signalling. (2016)

Elise Petit, Pierre-François Cartron, Lisa Oliver, François Vallette

  • Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth.
 Theranostics (2016)

Mathilde Cheray, Romain Pacaud, Arulraj Nadaradjane, Lisa Oliver, François Vallette, Pierre-François Cartron

  • Prostaglandin E2 plays a major role in glioma resistance and progression
 Translational Cancer Research (2016)

Lisa Oliver, Christophe Olivier, François M. Vallette

  • Low-Dose Pesticide Mixture Induces Senescence In Normal Mesenchymal Stem Cells (MSC) And Promotes Tumorigenic Phenotype In Premalignant MSC
 TStem Cells (2016)

Mazene Hochane, Valérie Trichet, Claire Pecqueur, Pierre Avril, Lisa Oliver, Jérôme Denis, Régis Brion, Jérôme Amiaud, Alain Pineau, Philippe Naveilhan, Dominique Heymann, François M. Vallette, Christophe Olivier

  • Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside
Oncotarget (2016)

Julien Fleurence, Denis Cochonneau, Sophie Fougeray, Lisa Oliver, Fanny Geraldo, Mickaël Terme, Mylène Dorvillius, Delphine Loussouarn, François Vallette, Francois Paris, Stéphane Birklé

  • Stereotaxic administrations of allogeneic human Vγ9Vδ2 T cells efficiently control the development of human glioblastoma brain tumors
Oncoimmunol., 2016, in press

Ulrich Jarry, Cynthia Chauvin, Noémie Joalland, Alexandra Léger, Sandrine Minault, Myriam Robard, Marc Bonneville, Lisa Oliver, François M. Vallette, Henri Vié, Claire Pecqueur-Hellman, Emmanuel Scotet.

  • FVB/N Mice Spontaneously Heal Ulcerative Lesions Induced by Mycobacterium ulcerans and Switch M. ulcerans into a Low Mycolactone Producer
 Journal of Immunology (2016)

Estelle Marion, Ulrich Jarry, Camille Cano, Caroline Savary, Céline Beauvillain, Marie Robbe-Saule, Laurence Pressier, Frédéric Altare, Yves Delneste, Pascale Jeannin, Laurent Marsollier

  • Clinical, Genetic and Innate Immunity Characteristics of Melanoma in Organ Transplant Recipients
Acta Dermato-Venereologica (2016)

A. Brocard, Ac. Knol, C. Bossard, M. Denis, G. Quereux, M. Saint-Jean, L. Peuvrel, Amir Khammari, G. Blancho, Jacques Dantal, Brigitte Dréno

  • RhoB Mediates Phosphoantigen Recognition by Vg9Vd2 T Cell Receptor
Cell Reports (2016)

Zsolt Sebestyen, Wouter Scheper, Anna Vyborova, Siyi Gu, Zuzana Rychnavska, Marleen Schiffler, Astrid Cleven, Coraline Chéneau, Martje Van Noorden, Cassie-Marie Peigné, Daniel Olive, Robert Jan Lebbink, Rimke Oostvogels, Tuna Mutis, Gerrit Jan Schuurhuis, Erin J. Adams, Emmanuel Scotet, Jürgen Kuball

  • Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine
Oncotarget (2016)

David Roulois, Sophie Deshayes, Marie-Noëlle Guilly, Joëlle Nader, Charly Liddell, Myriam Robard, Philippe Hulin, Amal Ouacher, Vanessa Le Martelot, Jean-François Fonteneau, Marc Grégoire, Christophe Blanquart, Daniel L. Pouliquen

  • Pleural Effusions from Patients with Mesothelioma Induce Recruitment of Monocytes and Their Differentiation into M2 Macrophages

 Journal of Thoracic Oncology (2016)

Anne-Laure Chéné, Sènan d’Almeida, Thibaut Blondy, Julie Tabiasco, Sophie Deshayes, Jean-François Fonteneau, Laurent Cellerin, Yves Delneste, Marc Grégoire, Christophe Blanquart

  • The ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27.
 OncoImmunology (2016)

Senan M. d’Almeida, Gilles Kauffenstein, Charlotte Roy, Laetitia Basset, Loukas Papargyris, Daniel Henrion, Véronique Catros, Norbert Ifrah, Philippe Descamps, Anne Croue, Pascale Jeannin, Marc Grégoire, Yves Delneste, Julie Tabiasco

  • The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer
 J Immunol. (2016)

Fonteneau JF, Brilot F, Münz C, Gannagé M.

  • Clusterin facilitates apoptotic cell clearance and prevents apoptotic cell-induced autoimmune responses
 Cell Death and Disease (2016)

P. Cunin, C. Beauvillain, C. Miot, J-F. Augusto, L. Preisser, S. Blanchard, P. Pignon, M. Scotet, E. Garo, I. Fremaux, A. Chevailler, J-F. Subra, P. Blanco, Mr Wilson, P. Jeannin, Y. Delneste.

  • The angiotensin II type 2 receptor activates flow-mediated outward remodeling through T cells-dependent interleukin-17 production
 Cardiovasc Res (2016)

Caillon A, Grenier C, Grimaud L, Vessieres E, Guihot AL, Blanchard S, Lelievre E, Chabbert M, Foucher ED, Jeannin P, Beauvillain C, Abraham P, Loufrani L, Delneste Y, Henrion D

  • Pleural Effusions from Patients with Mesothelioma Induce Recruitment of Monocytes and Their Differentiation into M2 Macrophages
 Journal of Thoracic Oncology (2016)

Anne-Laure Chéné, Sènan d’Almeida, Thibaut Blondy, Julie Tabiasco, Sophie Deshayes, Jean-François Fonteneau, Laurent Cellerin, Yves Delneste, Marc Grégoire, Christophe Blanquart.

  • The ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27
 OncoImmunology (2016)

Senan M. d’Almeida, Gilles Kauffenstein, Charlotte Roy, Laetitia Basset, Loukas Papargyris, Daniel Henrion, Véronique Catros, Norbert Ifrah, Philippe Descamps, Anne Croue, Pascale Jeannin, Marc Grégoire, Yves Delneste, Julie Tabiasco

  • FVB/N Mice Spontaneously Heal Ulcerative Lesions Induced by Mycobacterium ulcerans and Switch M. ulcerans into a Low Mycolactone Producer.
 Journal of Immunology (2016)

Estelle Marion, Ulrich Jarry, Camille Cano, Caroline Savary, Céline Beauvillain, Marie Robbe-Saule, Laurence Pressier, Frédéric Altare, Yves Delneste, Pascale Jeannin, Laurent Marsollier

  • BTN3A molecules considerably improve Vγ9Vδ2T cells-based immunotherapy in acute myeloid leukemia.
OncoImmunology (2016)

A. Benyamine, A. Le Roy, Emilie Mamessier, J. Gertner-Dardenne, C. Castanier, F. Orlanducci, L. Pouyet, A. Goubard, Y. Collette, N. Vey, Emmanuel Scotet, R. Castellano, D. Olive

  •  CD40L confers helper functions to human inra-melanoma clas-I-restricted CD4CD8 double positive Tcells
Oncoimmunol., 2016, in press

Parrot T, Oger R, Benlalam H, Raingeard de la Bletiere D, Jouand, N, Coutolleau A, Preissier L, Khammari A, Dreno B, Guardiola P, Delneste Y, Labarriere N, Gervois N

  • IRES-dependent translation of the long non coding RNA meloe in melanoma cells produces the most immunogenic MELOE antigens
 Oncotarget. 2016 Sep 13;7(37):59704-59713

Charpentier M, Croyal M, Carbonnelle D, Fortun A, Florenceau L, Rabu C, Krempf M, Labarrière N, Lang F

  • IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive T cells.
 Eur J Immunol. 2016  Jul;46(7):1770-82

Parrot T, Allard M, Oger R, Benlalam H, Raingeard de la Blétière D, Coutolleau A, Preisser L, Desfrançois J, Khammari A, Dréno B, Labarrière N, Delneste Y, Guardiola P, Gervois N

  • Prenylated polyphenols from Clusiaceae and Calophyllaceae with immunomodulatory activity on endothelial cells
Plos One 2016 Dec 1;11(12)

C. Rouger, S. Pagie, S. Derbré, A.-M. Le Ray, P. Richomme & B. Charreau

  • Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells
JCI Insight 2016

E. Picarda, S. Bézie, L. Boucault, E. Autrusseau, S. Kilens, D. Meistermann, B. Martinet, V. Daguin, A. Donnart, E. Charpentier, L. David, I. Anegon & C. Guillonneau

  • A composite score associated with spontaneous operational tolerance in kidney transplant recipients
Kidney International 2016

R. Danger, M. Chesneau, C. Paul, P. Guérif, M. Durand, K.A. Newell, S. Kanaparthi, L.A. Turka, J.-P. Soulillou, R. Houlgatte, M. Giral, G. Ramstein, S. Brouard

  • Preclinical testing of antihuman CD28 Fab’ antibody in a novel nonhuman primate small animal rodent model of xenogenic graft-versus-host disease
Transplantation 2016, Vol 100 – Number 12

Keli L. Hippen, Benjamin Watkins, Victor Tkachev, Amanda M. Lemire, Charles Lehnen, Megan J. Riddle, Karnail Singh, Angela Panoskaltsis-Mortari,
Bernard Vanhove, Jakub Tolar, Leslie S. Kean and Bruce R. Blazar

  • Renal operational tolerance is associated with a defect of blood Tfh cells that exhibit impaired B cell help
American Journal of Transplantation 2016 in press

A. Chenouard, M. Chesneau, L. B. Nguyen, S. Le Bot, M. Cadoux, E. Dugast, C. Paul, S. Malard-Castagnet, S. Ville, P. Guérif, J.-P. Soulillou, N. Degauque, R. Danger, M. Giral & S. Brouard

  • First-in-Man Study in Healthy Subjects with FR104, a pegylated Monoclonal Antibody Fragment Antagonist of CD28
The Journal of Immunology 2016 in press

N. Poirier, G. Blancho, M. Hiance, C. Mary, T. Van Assche, J. Lempoels, S. Ramael, W. Wang, V. Thépenier, C. Braudeau,?N. Salabert, R. Josien, I. Anderson, I. Gourley, J.-P. Soulillou, D. Coquoz & B. Vanhove

  • Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies
BMC Biotechnol 2016 in press

L.-H. Ouisse, L. Gautreau-Rolland, M.-C. Devilder, M. Osborn, M. Moyon, J. Visentin, F. Halary, M. Bruggemann, R. Buelow, I. Anegon & X. Saulquin

  • Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies
PeerJ 2016 in press

Lord P, Spiering R, Aguillon JC, Anderson AE, Appel S, Benitez-Ribas D, Ten Brinke A, Broere F, Cools N, Cuturi MC, Diboll J, Geissler EK, Giannoukakis N, Gregori S, van Ham SM, Lattimer S, Marshall L, Harry RA, Hutchinson JA, Isaacs JD, Joosten I, van Kooten C, Lopez Diaz de Cerio A, Nikolic T, Oral HB, Sofronic-Milosavljevic L, Ritter T, Riquelme P, Thomson AW, Trucco M, Vives-Pi M, Martinez-Caceres EM & Hilkens CM

Year 2015

  • A lineage-specific methylation pattern controls the transcription of the polycistronic mRNA coding MELOE melanoma antigens
Melanoma Res. 2015 Aug;25(4):279-83.

Chalopin B, Florenceau L, Fradin D, Labarrière N, Moreau-Aubry A

  • PD-1 expression conditions T cell avidity within an antigen-specific repertoire
Oncoimmunology. 2015 Oct 29;5(1):e1104448

Simon S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere N

  • Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells 
Plos One 2015 in press

Bezié S, Picarda E, Tesson L, Renaudin K, Durand J, Ménoret S, Mérieau E, Chiffoleau E, Guillonneau C, Caron L, Anegon I

  • Molecules and mechanisms implicated in the peculiar antigenic activation process of human Vy9Vd2T cells 
Front Immunol 2015 Jan 5;5:657

Harly C, Peigné CM, Scotet E

  • CD10 delineates a subset of human IL-4 producing follicular helper T cells involved in the survival of follicular lymphoma B cells
    Blood. 2015 Mar 2.

Amé-Thomas P, Hoeller S, Artchounin C, Misiak J, Braza MS, Jean R, Le Priol J, Monvoisin C, Martin N, Gaulard P, Tarte K

  • Radiation-induced PGE2 sustains human glioma cells growth and survival through EGF signaling
    Oncotarget. 2015 Mar 30;6(9):6840-9.

Brocard E, Oizel K, Lalier L, Pecqueur C, Paris F, Vallette FM, Oliver L.

  • Tolerant Kidney Transplant Patients Produce B Cells with Regulatory Properties.
    J Am Soc Nephrol. 2015 Feb 2.

Chesneau M, Michel L, Dugast E, Chenouard A, Baron D, Pallier A, Durand J, Braza F, Guerif P, Laplaud DA, Soulillou JP, Giral M, Degauque N, Chiffoleau E, Brouard S.

  • Efficacy of Myeloid Derived Suppressor Cells on Transplant Survival.
    Transplantation. 2015 Aug 12.

Guillonneau C.

  • IL-34 is a Treg-specific cytokine and mediates transplant tolerance
    J Clin Invest. 2015 Sep 21. pii: 81227. doi: 10.1172/JCI81227.

Bézie S, Picarda E, Ossart J, Tesson L, Usal C, Renaudin K, Anegon I, Guillonneau C.

Year 2014

  • Receptor activating NF-B ligand (RANKL) is a constitutiveintracellular protein in resting human basophils and is stronglyinduced on their surface by interleukin 3
Immunobiology 2014

Caroline Poli, Jérôme C. Martin, Cécile Braudeau, Gaelle Bériou,Caroline Hémont, Céline Charrier, Sarah Guérin,Michèle Heslan, Régis Josien

  • Differential expression of the immunosuppressive enzyme IL4l1 induce Aiolos+ but not natural Helios+, FOXP3+ Treg cells 
Eur. J Immunol 2014, Nov. 29

Scarlata CM, Celse C, Pignon P, Ayyoub M, Valmori D 

  • Advantages of Papio anubis for preclinical testing of immunotoxicity of candidate therapeutic antagonist antibodies targeting CD28 
MAbs. 2014 May-Jun;6(3):697-707

Poirier N, Mary C, Le Bas-Bernardet S, Daguin V, Belarif L, Chevalier M, Hervouet J, Minault D, Ville S, Charpy V, Blancho G, Vanhove B

  • Diagnostic criteria for autoimmune neutropenia
Autoimmun Rev 2014 Apr-May;13 (4-5):574-6

Youinou P, Jamin C, Le Pottier L, Renaudineau Y, Hillion S, Pers JO

  • Specific forms of BAFF favor BAFF receptor-mediated epithelial cell survival 
J Autoimmun. 2014 Jun;51:30-7

Lahiri A, Varin MM, Le Pottier L, Pochard P, Bendaoud B, Youinou P, Pers JO

  • The contribution of epigenetics in Sjögren’s syndrome
Front Genet.  2014 Apr 3;5:71

Konsta OD, Thabet Y, Le Dantec C, Brooks WH, Tzioufas AG, Pers JO, Renaudineau Y 

  • Annexin A2 autoantibodies in thrombosis and autoimmune diseases 
Thromb Res. 2014 Dec 13

Canas F, Simonin L, Couturaud F, Renaudineau Y 

  • IL-34 and M-CSF-induced macrophages switch memory T cells into Th17 cells via membrane IL-1a
Eur. J. Immunol 2014 Dec. 26

Foucher ED, Blanchard S, Preisser L, Descamps P, Ifrah N, Delneste Y, Jeannin P 

  • TLR9 expressed on plasma membrane acts as a negative regulator of human B cell response 
J.Autoimmun. 2014 Jun;51:23-9

Guerrier T, Pochard P, Lahiri A, Youinou P, Pers JO, Jamin C. 

  • Regulatory functions of B cells in allergic diseases 
Allergy 2014, Nov;69(11):1454-63

Braza F, Chesne J, Castagnet S, Magnan A, Brouard S 

  • The disintegrin and metalloproteinase ADAM10 mediates a canonical Notch-dependent regulation of IL-6 through DII4 in human endothelial cells 
Biochem Pharmacol. 2014, Oct 15;91(4):510-21

Pabois A, Devallière J, Quillard T, Coulon F, Gérard N, Laboisse C, Toquet C, Charreau B

  • DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus
Autoimmunity 2014, Jun;47(4):265-71

Fali T, Le Dantec C, Thabet Y, Jousse S, Hanrotel C, Youinou P, Brooks WH, Perl A, Renaudineau Y

  •  B cells dispay an abnormal distribution and an impaired suppressive function in patients with chronic antibody-mediated rejection 
Kidney Int.  2014 Mar;85(3):590-9

Nouël A, Ségalen I, Jamin C, Doucet L, Caillard S, Renaudineau Y, Pers JO, Le Meur Y, Hillion S. 

  •  Evaluation of the therapeutic potential of bone marrow-derived myeloid suppressor cell (MDSC) adoptive transfer in mouse models of autoimmunity and allograft rejection 
Plos One  2014 Jun 13;9(6):e100013

Drujont L, Carretero-Iglesia L, Bouchet-Delbos L, Beriou G, Merieau E, Hill M, Delneste Y, Cuturi C and Louvet C. 

  •  Unique B cell differentiation profile in tolerant kidney transplant patients.

    Am J Transplant. 2014 Jan;14(1):144-55.

    Chesneau M, Pallier A, Braza F, Lacombe G, Le Gallou S, Baron D, Giral M, Danger R, Guerif P, Aubert-Wastiaux H, Néel A, Michel L, Laplaud DA, Degauque N, Soulillou JP, Tarte K, Brouard S.

  • Regulatory B Cells: An Exciting Target for Future Therapeutics in Transplantation.

    Front Immunol. 2014 Jan 22;5:11.

    Nouël A1, Simon Q1, Jamin C2, Pers JO2, Hillion S2.

  • Regulatory B-cell supress T-cell proliferation through a TGF?/IDO axis and are deficient in chronic humoral rejection.

    Ann Rheum Dis. 2014 Mar 1;73 Suppl 1:A89.

    Nouël A, Segalen I, Jamin C, Pers JO, Le Meur Y, Hillion S.

  • Evaluation of the therapeutic potential of bone marrow-derived myeloid suppressor cell (MDSC) adoptive transfer in mouse models of autoimmunity and allograft rejection

    PLoS One. 2014 Jun 13;9(6):e100013.

    Lucile Drujont, Laura Carretero-Iglesia, Laurence Bouchet-Delbos, Gaelle Beriou, Emmanuel Merieau, Marcelo Hill, Yves Delneste, Maria Cristina Cuturi and Cedric Louvet.

  • Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid.

    Mucosal Immunol. 2014 Jan;7(1):101-13

    Martin JC, Bériou G, Heslan M, Chauvin C, Utriainen L, Aumeunier A, Scott CL, Mowat A, Cerovic V, Houston SA, Leboeuf M, Hubert FX, Hémont C, Merad M, Milling S, Josien R.

  • Soluble HLA-I/peptide monomers mediate antigen-specific CD8 T cell activation through passive peptide exchange with cell-bound HLA-I molecules

    J Immunol, 2014; 192:5090-5097

    Allard M, Oger R, Benlalam H, Florenceau L, Echasserieau K, Bernardeau K, Labarrière N, Lang F and Gervois N.

  • Autologous dendritic cells prolong allograft survival throughTmem176b-dependent antigen cross-presentation

    Am. J. Transplantation. 2014 May;14(5):1021-31

    Segovia M, Louvet C, Charnet P, Savina A, Tilly G, Gautreau L, Carretero-Iglesia C, Beriou G, Cebrian I, Cens T, Hepburn L, Chiffoleau E, Floto RA, Anegon I, Amigorena S, Hill M and Cuturi MC

  • MHC-derived allopeptide activates TCR-biased CD8+ Tregs and suppresses organ rejection

    J. Clin. Invest. 2014 Jun 2;124(6):2497-512.

    E. Picarda, S. Bézie, V. Venturi, K. Echasserieau, E. Merieau, A. Delhumeau, K. Renaudin, S. Brouard, K. Bernardeau, I. Anegon and C. Guillonneau

  • Heme oxygenase-1 as a target for the design of gene and pharmaceutical therapies for autoimmune diseases.Curr Gene Ther. 2014;14(3):218-35Mackern-Oberti JP, Riquelme SA, Llanos C, Schmidt CB, Simon T, Anegon I, Jara E, Riedel CA, Bueno SM, Kalergis AM.
  • The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures.Sci Rep. 2014 Mar 18;4:4230.Pacaud R, Brocard E, Lalier L, Hervouet E, Vallette FM, Cartron PF.
  • DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-)methylation of TRAF1Biochimie. 2014 Sep;104:36-49.Pacaud R, Sery Q, Oliver L, Vallette FM, Tost J, Cartron PF.
  • IL-34 and macrophage colony-stimulating factor are overexpressed in hepatitis C virus fibrosis and induce profibrotic macrophages that promote collagen synthesis by hepatic stellate cells.Hepatology. 2014 Dec;60(6):1879-90.Preisser L, Miot C, Le Guillou-Guillemette H, Beaumont E, Foucher ED, Garo E, Blanchard S, Frémaux I, Croué A, Fouchard I, Lunel-Fabiani F, Boursier J, Roingeard P, Calès P, Delneste Y, Jeannin P
  • The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vγ9Vδ2 T cells
    Immunity. 2014 Apr 17;40(4):490-500.Sandstrom A, Peigné CM, Léger A, Crooks JE, Konczak F, Gesnel MC, Breathnach R, Bonneville M, Scotet E*, Adams EJ*. 

Year 2013

  • Overexpression of meloe gene in melanomas is controlled both by specific transcription factors and hypomethylation

PLoS One. 2013 25 8(9): e75421.

Bobinet M, Vignard V, Florenceau L, Lang F, Labarriere N, Moreau-Aubry A

  • B cells display an abnormal distribution and an impaired suppressive function in patients with chronic antibody-mediated rejection.

    Kidney Int. 2013 Nov 27. doi: 10.1038/ki.2013.457.

    Nouël A, Ségalen I, Jamin C, Doucet L, Caillard S, Renaudineau Y, Pers JO, Le Meur Y, Hillion S. SourceEA2216 ‘Immunology and Pathology’ Université de Brest, SFR ScinBios, LabEx IGO ‘Immunotherapy Graft, Oncology’, Brest, France.

  • Regulatory B Cells and Tolerance in Transplantation: From Animal Models to Human

    Front Immunol. 2013 Dec 31;4:497.

    Chesneau M, Michel L, Degauque N, Brouard S.

  • Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases.

    FASEB J. 2013 Feb;27(2):703-11.

    Ménoret S, Fontanière S, Jantz D, Tesson L, Thinard R, Rémy S, Usal C, Ouisse LH, Fraichard A, Anegon I.

  • A full GMP process to select and amplify epitope-specific T lymphocytes for adoptive immunotherapy of metastatic melanoma.

    Clin Dev Immunol. 2013;2013:932318.

    Labarriere N, Fortun A, Bellec A, Khammari A, Dreno B, Saïagh S, Lang F.

  • Repeated Systemic Administrations of Both Aminobisphosphonates and Human Vg9Vd2 T Cells Efficiently Control Tumor Development In Vivo

    J Immunol 2013, 191:1993-2000.

    Thibault Santolaria, Myriam Robard, Alexandra Léger, Véronique Catros, Marc Bonneville and Emmanuel Scotet.

  • Specific inhibition of one DNMT1-including complex influences tumor initiation and progression.Clin Epigenetics. 2013 Jun 28;5(1):9Cheray M, Pacaud R, Nadaradjane A, Vallette FM, Cartron PF.
  • IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ

PLoS One. 2013;8(2):e56045.Foucher ED, Blanchard S, Preisser L, Garo E, Ifrah N, Guardiola P, Delneste Y, Jeannin P. 

  • The melanoma antigens MELOE-1 and MELOE-2 are translated from a bona fide polycistronic mRNA containing functional IRES sequencesPLoS One. 2013 25;8(9): e75233 – Carbonnelle D, Vignard V, Sehedic D, Moreau-Aubry A, Florenceau L, Charpentier M, Mikulits W, Labarriere N, Lang F